I just like the big words

Remeron (mirtazapine).

Side effects include sedation, orthostatic hypotension, anticholinergic symptoms, and weight gain. The risk of agranulocytosis/granulocytopenia is around 1/1000. In Finland, regular WBC monitoring is recommended within the 2 first months of treatment with mianserin because of 67 cases of granulocytopenia or agranulocytosis in Finland between 1981-94 (the population of Finland is only 5 million...). There have been about 20 fatal cases and also cases of pancytopenia (aplastic anaemia). weight gain was clinically significant in 12% of patients in clinical trials (versus 2% for placebo). About a year ago I described a case of a severely depressed woman in her sixties who became psychotic (masturbated with a toothpaste tube, stated I had instructed her to do this, etc) while on mirtazapine 45 mg daily (she had also just been withdrawn from lamotrigine). I had a young patient with advanced AIDS (and probably some AIDS dementia) who developed visual hallucinations when I increased his mirtazapine from 15 to 30 mg. The official product info says edema occurs in 1% of patients... The idea being (at least in theory) that at higher doses the increased noradrenergic tone (secondary to alpha-2 receptor antagonism) would offset the increased appetite (presumed to be due to antihistaminergic effect). This is similar to the decreased sedation noted as the dose is increased to >= 30 mg/day. A few months ago I put a patient on Remeron (mirtazapine). She called me two days later saying that she had developed severe cramps in her legs and stopped taking it. Yesterday another young patient mentioned the same problem. Remeron is closely related to mianserin (Tolvon). With mianserin, some patients develop paradoxical agitation, and the symptoms can include restless legs-like phenomenon, especially at night. It is probably due to noradrenergic stimulation. If you experience any of the following serious side effects, stop taking mirtazapine and call your doctor immediately or seek emergency medical treatment: · an allergic reaction (swelling of the lips, face, or tongue; difficulty breathing); · seizures; · a fast or irregular heartbeat; or · fever, chills, a sore throat, flu-like symptoms, or sores in your mouth or nose. • Other, less serious side effects may be more likely to occur. Continue to take mirtazapine and talk to your doctor if you experience · drowsiness; · nausea; · increase in weight or appetite; · dizziness; · dry mouth; · constipation; or · mild tremor.

I just like the big words

Remeron (mirtazapine).

Side effects include sedation, orthostatic hypotension, anticholinergic symptoms, and weight gain. The risk of agranulocytosis/granulocytopenia is around 1/1000. In Finland, regular WBC monitoring is recommended within the 2 first months of treatment with mianserin because of 67 cases of granulocytopenia or agranulocytosis in Finland between 1981-94 (the population of Finland is only 5 million...). There have been about 20 fatal cases and also cases of pancytopenia (aplastic anaemia). weight gain was clinically significant in 12% of patients in clinical trials (versus 2% for placebo). About a year ago I described a case of a severely depressed woman in her sixties who became psychotic (masturbated with a toothpaste tube, stated I had instructed her to do this, etc) while on mirtazapine 45 mg daily (she had also just been withdrawn from lamotrigine). I had a young patient with advanced AIDS (and probably some AIDS dementia) who developed visual hallucinations when I increased his mirtazapine from 15 to 30 mg. The official product info says edema occurs in 1% of patients... The idea being (at least in theory) that at higher doses the increased noradrenergic tone (secondary to alpha-2 receptor antagonism) would offset the increased appetite (presumed to be due to antihistaminergic effect). This is similar to the decreased sedation noted as the dose is increased to >= 30 mg/day. A few months ago I put a patient on Remeron (mirtazapine). She called me two days later saying that she had developed severe cramps in her legs and stopped taking it. Yesterday another young patient mentioned the same problem. Remeron is closely related to mianserin (Tolvon). With mianserin, some patients develop paradoxical agitation, and the symptoms can include restless legs-like phenomenon, especially at night. It is probably due to noradrenergic stimulation. If you experience any of the following serious side effects, stop taking mirtazapine and call your doctor immediately or seek emergency medical treatment: · an allergic reaction (swelling of the lips, face, or tongue; difficulty breathing); · seizures; · a fast or irregular heartbeat; or · fever, chills, a sore throat, flu-like symptoms, or sores in your mouth or nose. • Other, less serious side effects may be more likely to occur. Continue to take mirtazapine and talk to your doctor if you experience · drowsiness; · nausea; · increase in weight or appetite; · dizziness; · dry mouth; · constipation; or · mild tremor.

(no subject)

FactCheck.org - Bush's 16 Words on Iraq & Uranium - He May Have Been Wrong But He Wasn't Lying

Which is not to say that they weren't doing everything in their power to see the reality the way they wanted it to be. It'll be ironic if Rove goes down the toilet over this.

Starting multiple wars that kills tens of thousands of people is fully supported by the media, but blowjobs or outing of a single agent is cause for a serious look at the presidency.

(no subject)

FactCheck.org - Bush's 16 Words on Iraq & Uranium - He May Have Been Wrong But He Wasn't Lying

Which is not to say that they weren't doing everything in their power to see the reality the way they wanted it to be. It'll be ironic if Rove goes down the toilet over this.

Starting multiple wars that kills tens of thousands of people is fully supported by the media, but blowjobs or outing of a single agent is cause for a serious look at the presidency.

(no subject)

mk; am pretty sure the nebu blogspots are caused by milky treats; no more wee amounts of milk or cheese. this may traumatize him, as he can be dead asleep in the basement and hear a tiny cheese wrapper crinkle, and gallumph desperately to the top of the stairs in 0.00 seconds. (cheese-like wrappers that wrap things other than cheese mysteriously don't affect him - i suspect a single cheese molecule zips its way through the air and finds its way to his nose.)

(no subject)

mk; am pretty sure the nebu blogspots are caused by milky treats; no more wee amounts of milk or cheese. this may traumatize him, as he can be dead asleep in the basement and hear a tiny cheese wrapper crinkle, and gallumph desperately to the top of the stairs in 0.00 seconds. (cheese-like wrappers that wrap things other than cheese mysteriously don't affect him - i suspect a single cheese molecule zips its way through the air and finds its way to his nose.)